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A Novel Hydroxylation Step in the Taxane Biosynthetic Pathway: A New Approach to Paclitaxel Production by Synthetic Biology
Engineered plant cell lines have the potential to achieve enhanced metabolite production rates, providing a high-yielding source of compounds of interest. Improving the production of taxanes, pharmacologically valuable secondary metabolites of Taxus spp., is hindered by an incomplete knowledge of th...
Autores principales: | Sanchez-Muñoz, Raul, Perez-Mata, Edgar, Almagro, Lorena, Cusido, Rosa M., Bonfill, Mercedes, Palazon, Javier, Moyano, Elisabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247824/ https://www.ncbi.nlm.nih.gov/pubmed/32528936 http://dx.doi.org/10.3389/fbioe.2020.00410 |
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