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Icariin Improves Age-Related Testicular Dysfunction by Alleviating Sertoli Cell Injury via Upregulation of the ERα/Nrf2-Signaling Pathway

Sertoli cells play crucial roles in spermatogenesis and are impaired by aging. Icariin, a flavonoid from Epimedium, has been reported to exhibit anti-aging effects and improve testicular dysfunction in the clinical setting. However, whether icariin improves age-related degeneration of testicular fun...

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Detalles Bibliográficos
Autores principales: Zhao, Haixia, You, Xu, Chen, Qian, Yang, Siqi, Ma, Qiongyan, He, Yumin, Liu, Chaoqi, Dun, Yaoyan, Wu, Jie, Zhang, Changcheng, Yuan, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247842/
https://www.ncbi.nlm.nih.gov/pubmed/32528279
http://dx.doi.org/10.3389/fphar.2020.00677