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Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer’s Disease

Chronic neuroinflammation has long been hypothesized to be involved in Alzheimer’s Disease (AD) progression. Previous research suggests that both anti-inflammatory and inflammatory microglia ameliorate amyloid pathology, but the latter worsen tau pathology. In this study, we sought to determine whet...

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Detalles Bibliográficos
Autores principales: Dionisio-Santos, Dawling A., Behrouzi, Adib, Olschowka, John A., O’Banion, M. Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247853/
https://www.ncbi.nlm.nih.gov/pubmed/32528242
http://dx.doi.org/10.3389/fnins.2020.00441