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Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds

Matrix deposition is essential for wound repair, but when excessive, leads to hypertrophic scars and fibrosis. The factors that control matrix deposition in skin wounds have only partially been identified and the consequences of matrix alterations for the mechanical properties of wounds are largely...

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Detalles Bibliográficos
Autores principales: Wietecha, Mateusz S., Pensalfini, Marco, Cangkrama, Michael, Müller, Bettina, Jin, Juyoung, Brinckmann, Jürgen, Mazza, Edoardo, Werner, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248062/
https://www.ncbi.nlm.nih.gov/pubmed/32451392
http://dx.doi.org/10.1038/s41467-020-16409-z