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Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds
Matrix deposition is essential for wound repair, but when excessive, leads to hypertrophic scars and fibrosis. The factors that control matrix deposition in skin wounds have only partially been identified and the consequences of matrix alterations for the mechanical properties of wounds are largely...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248062/ https://www.ncbi.nlm.nih.gov/pubmed/32451392 http://dx.doi.org/10.1038/s41467-020-16409-z |