CCR3 antagonist protects against induced cellular senescence and promotes rejuvenation in periodontal ligament cells for stimulating pulp regeneration in the aged dog

Pulp regeneration after transplantation of mobilized dental pulp stem cells (MDPSCs) declines in the aged dogs due in part to the chronic inflammation and/or cellular senescence. Eotaxin-1/C-C motif chemokine 11 (CCL11) is an inflammation marker via chemokine receptor 3 (CCR3). Moreover, CCR3 antago...

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Detalles Bibliográficos
Autores principales: Zayed, Mohammed, Iohara, Koichiro, Watanabe, Hideto, Nakashima, Misako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248074/
https://www.ncbi.nlm.nih.gov/pubmed/32451381
http://dx.doi.org/10.1038/s41598-020-65301-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248074/
https://www.ncbi.nlm.nih.gov/pubmed/32451381
http://dx.doi.org/10.1038/s41598-020-65301-9

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