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A Method for Identification of the Methylation Level of CpG Islands From NGS Data

In the course of sample preparation for Next Generation Sequencing (NGS), DNA is fragmented by various methods. Fragmentation shows a persistent bias with regard to the cleavage rates of various dinucleotides. With the exception of CpG dinucleotides the previously described biases were consistent wi...

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Detalles Bibliográficos
Autores principales: Uroshlev, Leonid A., Abdullaev, Eldar T., Umarova, Iren R., Il’icheva, Irina A., Panchenko, Larisa A., Polozov, Robert V., Kondrashov, Fyodor A., Nechipurenko, Yury D., Grokhovsky, Sergei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248081/
https://www.ncbi.nlm.nih.gov/pubmed/32451390
http://dx.doi.org/10.1038/s41598-020-65406-1