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Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures

Each polymerase nucleotide addition cycle is associated with two primary conformational changes of the catalytic complex: the pre-chemistry active site closure and post-chemistry translocation. While active site closure is well interpreted by numerous crystallographic snapshots, translocation interm...

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Detalles Bibliográficos
Autores principales: Wang, Meihua, Li, Rui, Shu, Bo, Jing, Xuping, Ye, Han-Qing, Gong, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248106/
https://www.ncbi.nlm.nih.gov/pubmed/32451382
http://dx.doi.org/10.1038/s41467-020-16234-4