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Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures
Each polymerase nucleotide addition cycle is associated with two primary conformational changes of the catalytic complex: the pre-chemistry active site closure and post-chemistry translocation. While active site closure is well interpreted by numerous crystallographic snapshots, translocation interm...
Autores principales: | Wang, Meihua, Li, Rui, Shu, Bo, Jing, Xuping, Ye, Han-Qing, Gong, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248106/ https://www.ncbi.nlm.nih.gov/pubmed/32451382 http://dx.doi.org/10.1038/s41467-020-16234-4 |
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