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Hydroxy-epoxide and keto-epoxide derivatives of linoleic acid activate trigeminal neurons

Endogenous lipid mediators are proposed to contribute to headache and facial pain by activating trigeminal neurons (TN). We recently identified 11-hydroxy-epoxide- and 11-keto-epoxide derivatives of linoleic acid (LA) that are present in human skin and plasma and potentially contribute to nociceptio...

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Detalles Bibliográficos
Autores principales: Doolen, Suzanne, Keyes, Gregory S., Ramsden, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248286/
https://www.ncbi.nlm.nih.gov/pubmed/32478201
http://dx.doi.org/10.1016/j.ynpai.2020.100046