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Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss

Aging is a process characterized by cognitive impairment and mitochondrial dysfunction. In neurons, these organelles are classified as synaptic and non-synaptic mitochondria depending on their localization. Interestingly, synaptic mitochondria from the cerebral cortex accumulate more damage and are...

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Detalles Bibliográficos
Autores principales: Olesen, Margrethe A., Torres, Angie K., Jara, Claudia, Murphy, Michael P., Tapia-Rojas, Cheril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248293/
https://www.ncbi.nlm.nih.gov/pubmed/32447261
http://dx.doi.org/10.1016/j.redox.2020.101558