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Premature synaptic mitochondrial dysfunction in the hippocampus during aging contributes to memory loss
Aging is a process characterized by cognitive impairment and mitochondrial dysfunction. In neurons, these organelles are classified as synaptic and non-synaptic mitochondria depending on their localization. Interestingly, synaptic mitochondria from the cerebral cortex accumulate more damage and are...
Autores principales: | Olesen, Margrethe A., Torres, Angie K., Jara, Claudia, Murphy, Michael P., Tapia-Rojas, Cheril |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248293/ https://www.ncbi.nlm.nih.gov/pubmed/32447261 http://dx.doi.org/10.1016/j.redox.2020.101558 |
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