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Localization Preference of Antimicrobial Peptides on Liquid-Disordered Membrane Domains

We performed coarse-grained simulations of the antimicrobial peptides Magainin-2, BP100, MSI-103, and MSI-78 on a phase-separated membrane to study their preference for the different domains. All the peptides displayed a clear preference for the liquid-disordered (Ld) phase over the liquid-ordered (...

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Detalles Bibliográficos
Autores principales: Su, Juanjuan, Marrink, Siewert J., Melo, Manuel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248343/
https://www.ncbi.nlm.nih.gov/pubmed/32509780
http://dx.doi.org/10.3389/fcell.2020.00350