Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory Effects

Scleroderma (SSc) is an autoimmune connective tissue disease characterized by immune dysregulation, vasculopathy, and fibrosis. We have previously demonstrated that low Fli1 expression in SSc fibroblasts and endothelial cells plays an important role in SSc pathogenesis. Cells of myeloid and lymphoid...

Descripción completa

Detalles Bibliográficos
Autores principales: Bujor, Andreea M., El Adili, Fatima, Parvez, Arshi, Marden, Grace, Trojanowska, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248379/
https://www.ncbi.nlm.nih.gov/pubmed/32508810
http://dx.doi.org/10.3389/fimmu.2020.00800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248379/
https://www.ncbi.nlm.nih.gov/pubmed/32508810
http://dx.doi.org/10.3389/fimmu.2020.00800

Ejemplares similares