A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids

Cyclic peptide-peptoid hybrids possess improved stability and selectivity over linear peptides and are thus better drug candidates. However, their synthesis is far from trivial and is usually difficult to automate. Here we describe a new rapid and efficient approach for the synthesis of click-based...

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Detalles Bibliográficos
Autores principales: Samarasimhareddy, Mamidi, Shamir, Mai, Shalev, Deborah E., Hurevich, Mattan, Friedler, Assaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248394/
https://www.ncbi.nlm.nih.gov/pubmed/32509731
http://dx.doi.org/10.3389/fchem.2020.00405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248394/
https://www.ncbi.nlm.nih.gov/pubmed/32509731
http://dx.doi.org/10.3389/fchem.2020.00405

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