Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis

BACKGROUND: BMP9, originating from the liver, and BMP10 are circulating BMPs that preserve vascular endothelial integrity. We assessed BMP9, BMP10 and soluble endoglin (sEng) levels and their relationships to liver disease severity and associated pulmonary vascular syndromes in a cohort of well-char...

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Detalles Bibliográficos
Autores principales: Owen, Nicola E., Alexander, Graeme J., Sen, Sambit, Bunclark, Katherine, Polwarth, Gary, Pepke-Zaba, Joanna, Davenport, Anthony P., Morrell, Nicholas, W., Upton, Paul. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248419/
https://www.ncbi.nlm.nih.gov/pubmed/32454407
http://dx.doi.org/10.1016/j.ebiom.2020.102794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248419/
https://www.ncbi.nlm.nih.gov/pubmed/32454407
http://dx.doi.org/10.1016/j.ebiom.2020.102794

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