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Mammalian STE20-like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2-mediated mitophagy

Mammalian STE20-like kinase 1 (MST1) plays an important role in pancreatic cancer progression, but its downstream targets are still unknown. In the present study, our results indicated that MST1 expression was significantly downregulated in pancreatic cancer cell lines (PANC-1, BxPC-3 and HPAC) comp...

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Detalles Bibliográficos
Autores principales: Hu, Yongli, Wang, Bing, Wang, Lie, Wang, Zhenran, Jian, Zhiyuan, Deng, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248474/
https://www.ncbi.nlm.nih.gov/pubmed/32377725
http://dx.doi.org/10.3892/mmr.2020.11098