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Coenzyme Q10 alleviates sevoflurane-induced neuroinflammation by regulating the levels of apolipoprotein E and phosphorylated tau protein in mouse hippocampal neurons

Sevoflurane may exert neurotoxic effects on the developing brain. Coenzyme Q10 (CoQ10) has been reported to reduce sevoflurane anesthesia-induced cognitive deficiency in 6-day-old mice. However, its specific mechanisms remain unknown. Apolipoprotein E (ApoE) has been reported to lead to the initiati...

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Detalles Bibliográficos
Autores principales: Yang, Man, Lian, Naqi, Yu, Yang, Wang, Yaoqi, Xie, Keliang, Yu, Yonghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248477/
https://www.ncbi.nlm.nih.gov/pubmed/32377738
http://dx.doi.org/10.3892/mmr.2020.11131