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Ginsenoside metabolite 20(S)-protopanaxadiol promotes neural stem cell transition from a state of proliferation to differentiation by inducing autophagy and cell cycle arrest

20(S)-Protopanaxadiol (PPD) is an active ginseng metabolite and is the final form of protopanaxadiol saponins metabolized by human intestinal microflora. The neuroprotective effects and mechanisms underlying PPD on neural stem cells (NSCs) are not completely understood. The aim of the present study...

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Detalles Bibliográficos
Autores principales: Chen, Shali, He, Ji, Qin, Xiyuan, Luo, Tiao, Pandey, Aparna, Li, Jijia, Liu, Suyou, Luo, Junli, Wang, Qi, Luo, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248512/
https://www.ncbi.nlm.nih.gov/pubmed/32319663
http://dx.doi.org/10.3892/mmr.2020.11081