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Dexmedetomidine alleviated sepsis-induced myocardial ferroptosis and septic heart injury

Cardiac dysfunction resulting from sepsis may cause significant morbidity and mortality, and ferroptosis plays a role in this pathology. Dexmedetomidine (Dex), a α2-adrenergic receptor (α2-AR) agonist exerts cardioprotective effects against septic heart dysfunction, but the exact mechanism is unknow...

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Detalles Bibliográficos
Autores principales: Wang, Chunyan, Yuan, Wenlin, Hu, Anmin, Lin, Juan, Xia, Zhengyuan, Yang, Catherine F., Li, Yalan, Zhang, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248514/
https://www.ncbi.nlm.nih.gov/pubmed/32377745
http://dx.doi.org/10.3892/mmr.2020.11114