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Effect of VX-765 on the transcriptome profile of mice spinal cords with acute injury

Previous studies have shown that caspase-1 plays an important role in the acute inflammatory response of spinal cord injury (SCI). VX-765, a novel and irreversible caspase-1 inhibitor, has been reported to effectively intervene in inflammation. However, the effect of VX-765 on genome-wide transcript...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Chen, Yu-Qing, Wang, Sai-Nan, Duan, Fei-Xiang, Shi, Yu-Jiao, Ding, Shu-Qin, Hu, Jian-Guo, Lü, He-Zuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248530/
https://www.ncbi.nlm.nih.gov/pubmed/32377730
http://dx.doi.org/10.3892/mmr.2020.11129