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Ischemic postconditioning attenuates the inflammatory response in ischemia/reperfusion myocardium by upregulating miR-499 and inhibiting TLR2 activation

Toll-like receptor 2 (TLR2)-mediated myocardial inflammation serves an important role in promoting myocardial ischemic/reperfusion (I/R) injury. Previous studies have shown that miR-499 is critical for cardioprotection after ischemic postconditioning (IPostC). Therefore, the present study evaluated...

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Detalles Bibliográficos
Autores principales: Zhang, Xin-Yue, Huang, Zheng, Li, Qing-Jie, Zhong, Guo-Qiang, Meng, Jian-Jun, Wang, Dong-Xiao, Tu, Rong-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248531/
https://www.ncbi.nlm.nih.gov/pubmed/32377693
http://dx.doi.org/10.3892/mmr.2020.11104