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Role of the PGE(2) receptor subtypes EP1, EP2, and EP3 in repetitive traumatic brain injury

AIMS: The goal was to explore the signaling pathways of PGE(2) to investigate therapeutic effects against secondary injuries following TBI. METHODS: Young (4.9 ± 1.0 months) and aged (20.4 ± 1.4 months) male wild type (WT) C57BL/6 and PGE(2) EP1, 2, and 3 receptor knockout mice were selected to eith...

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Detalles Bibliográficos
Autores principales: Catlin, James, Leclerc, Jenna L., Shukla, Krunal, Marini, Sarah M., Doré, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248542/
https://www.ncbi.nlm.nih.gov/pubmed/31617678
http://dx.doi.org/10.1111/cns.13228