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The association between PON1 and GSTM1 genetic variation with methylation of p16 gene promoter among Javanese farmers exposed to pesticides at Magelang Regency, Central Java, Indonesia

Occupational exposure to pesticides leads to the development of cancer. Aberrant DNA methylation plays a crucial role in cancer. The manifestation of the carcinogenic effect of pesticides could be determined by the variation of genes encoding enzyme, including PON1 Q192R and GSTM1. The goal of this...

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Detalles Bibliográficos
Autores principales: Ratna, Maya G., Nugrahaningsih, Dwi A.A., Sholikhah, Eti N., Dwianingsih, Ery K., Malueka, Rusdy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248662/
https://www.ncbi.nlm.nih.gov/pubmed/32478190
http://dx.doi.org/10.1016/j.heliyon.2020.e03993