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Mechanism of aspirin-induced inhibition on the secondary hyperalgesia in osteoarthritis model rats

AIMS: The daily activity of osteoarthritis (OA) patients is limited by chronic pain and central sensitization. Although non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are the first-line drugs for the treatment of OA-related pain, their efficacy on central sensitization remains uncl...

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Detalles Bibliográficos
Autores principales: Niibori, Mizuho, Kudo, Yasushi, Hayakawa, Takuya, Ikoma-Seki, Keiko, Kawamata, Ryosuke, Sato, Atsushi, Mizumura, Kazue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248669/
https://www.ncbi.nlm.nih.gov/pubmed/32478188
http://dx.doi.org/10.1016/j.heliyon.2020.e03963