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Mechanism of aspirin-induced inhibition on the secondary hyperalgesia in osteoarthritis model rats
AIMS: The daily activity of osteoarthritis (OA) patients is limited by chronic pain and central sensitization. Although non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are the first-line drugs for the treatment of OA-related pain, their efficacy on central sensitization remains uncl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248669/ https://www.ncbi.nlm.nih.gov/pubmed/32478188 http://dx.doi.org/10.1016/j.heliyon.2020.e03963 |