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Mechanism of aspirin-induced inhibition on the secondary hyperalgesia in osteoarthritis model rats

AIMS: The daily activity of osteoarthritis (OA) patients is limited by chronic pain and central sensitization. Although non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen are the first-line drugs for the treatment of OA-related pain, their efficacy on central sensitization remains uncl...

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Detalles Bibliográficos
Autores principales:	Niibori, Mizuho, Kudo, Yasushi, Hayakawa, Takuya, Ikoma-Seki, Keiko, Kawamata, Ryosuke, Sato, Atsushi, Mizumura, Kazue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248669/ https://www.ncbi.nlm.nih.gov/pubmed/32478188 http://dx.doi.org/10.1016/j.heliyon.2020.e03963

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