Efficient Access to 3,5-Disubstituted 7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidines Involving S(N)Ar and Suzuki Cross-Coupling Reactions

An efficient and original synthesis of various 3,5-disubstituted 7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidines is reported. A library of compounds diversely substituted in C-3 and C-5 positions was easily prepared from a common starting material, 3-bromo-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5...

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Detalles Bibliográficos
Autores principales: Jismy, Badr, Tikad, Abdellatif, Akssira, Mohamed, Guillaumet, Gérald, Abarbri, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248703/
https://www.ncbi.nlm.nih.gov/pubmed/32354132
http://dx.doi.org/10.3390/molecules25092062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248703/
https://www.ncbi.nlm.nih.gov/pubmed/32354132
http://dx.doi.org/10.3390/molecules25092062

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