Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole–Indole Conjugates as Anticancer CDK Inhibitors

On account of their overexpression in a wide range of human malignancies, cyclin-dependent kinases (CDKs) are among the most validated cancer targets, and their inhibition has been featured as a valuable strategy for anticancer drug discovery. In this study, a hybrid pharmacophore approach was adopt...

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Detalles Bibliográficos
Autores principales: Al-Warhi, Tarfah, El Kerdawy, Ahmed M., Aljaeed, Nada, Ismael, Omnia E., Ayyad, Rezk R., Eldehna, Wagdy M., Abdel-Aziz, Hatem A., Al-Ansary, Ghada H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248897/
https://www.ncbi.nlm.nih.gov/pubmed/32349307
http://dx.doi.org/10.3390/molecules25092031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248897/
https://www.ncbi.nlm.nih.gov/pubmed/32349307
http://dx.doi.org/10.3390/molecules25092031

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