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Predicting Drug Resistance Using Deep Mutational Scanning

Drug resistance is a major healthcare challenge, resulting in a continuous need to develop new inhibitors. The development of these inhibitors requires an understanding of the mechanisms of resistance for a critical mass of occurrences. Recent genome editing technologies based on high-throughput DNA...

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Detalles Bibliográficos
Autores principales: Pines, Gur, Fankhauser, Reilly G., Eckert, Carrie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248951/
https://www.ncbi.nlm.nih.gov/pubmed/32403408
http://dx.doi.org/10.3390/molecules25092265