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APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway

Hepatocellular carcinoma (HCC) is one of the most prevalent human malignancies worldwide and has high morbidity and mortality. Elucidating the molecular mechanisms underlying HCC recurrence and metastasis is critical to identify new therapeutic targets. This study aimed to determine the roles of ami...

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Detalles Bibliográficos
Autores principales: Zhai, Mengying, Yang, Zixia, Zhang, Chenrui, Li, Jinping, Jia, Jing, Zhou, Lingyi, Lu, Rong, Yao, Zhi, Fu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249043/
https://www.ncbi.nlm.nih.gov/pubmed/32457292
http://dx.doi.org/10.1038/s41419-020-2610-1