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Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies

Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages. Therapeutic mAbs are sequence modified from the wild type IgG isoforms to varying ext...

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Detalles Bibliográficos
Autores principales: Hollowell, Peter, Li, Zongyi, Hu, Xuzhi, Ruane, Sean, Kalonia, Cavan, van der Walle, Christopher F., Lu, Jian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249052/
https://www.ncbi.nlm.nih.gov/pubmed/32353995
http://dx.doi.org/10.3390/molecules25092047