Cargando…
Recent Advances in Studying Interfacial Adsorption of Bioengineered Monoclonal Antibodies
Monoclonal antibodies (mAbs) are an important class of biotherapeutics; as of 2020, dozens are commercialized medicines, over a hundred are in clinical trials, and many more are in preclinical developmental stages. Therapeutic mAbs are sequence modified from the wild type IgG isoforms to varying ext...
Autores principales: | Hollowell, Peter, Li, Zongyi, Hu, Xuzhi, Ruane, Sean, Kalonia, Cavan, van der Walle, Christopher F., Lu, Jian R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249052/ https://www.ncbi.nlm.nih.gov/pubmed/32353995 http://dx.doi.org/10.3390/molecules25092047 |
Ejemplares similares
-
Investigating the Orientation of an Interfacially
Adsorbed Monoclonal Antibody and Its Fragments Using Neutron Reflection
por: Ruane, Sean, et al.
Publicado: (2023) -
Competitive Adsorption of a Monoclonal Antibody and
Nonionic Surfactant at the PDMS/Water Interface
por: Shen, Kangcheng, et al.
Publicado: (2023) -
Understanding
the Stabilizing Effect of Histidine
on mAb Aggregation: A Molecular Dynamics Study
por: Saurabh, Suman, et al.
Publicado: (2022) -
Recent Advances in Kidney Bioengineering
por: Cintron Pregosin, Nina, et al.
Publicado: (2021) -
Bioengineering and computational analysis of programmed cell death ligand-1 monoclonal antibody
por: Kalim, Muhammad, et al.
Publicado: (2022)