Simplified Procedure for General Synthesis of Monosubstituted Piperazines—From a Batch Reaction Vessel to a Flow (Microwave) Reactor

We reported a novel simplified synthetic procedure for the preparation of monosubstituted piperazine derivatives which can now be easily prepared in a one-pot-one-step way from a protonated piperazine with no need of introduction of a protecting group. Reactions, proceeding either at room or higher...

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Detalles Bibliográficos
Autores principales: Němečková, Dana, Havránková, Eva, Šimbera, Jan, Ševčík, Richard, Pazdera, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249161/
https://www.ncbi.nlm.nih.gov/pubmed/32384633
http://dx.doi.org/10.3390/molecules25092168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249161/
https://www.ncbi.nlm.nih.gov/pubmed/32384633
http://dx.doi.org/10.3390/molecules25092168

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