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Intermittent peripheral exposure to lipopolysaccharide induces exploratory behavior in mice and regulates brain glial activity in obese mice

BACKGROUND: Consecutive peripheral immune challenges can modulate the responses of brain resident microglia to stimuli. High-fat diet (HFD) intake has been reported to stimulate the activation of astrocytes and microglia in the arcuate nucleus (ARC) of the hypothalamus in obese rodents and humans. H...

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Detalles Bibliográficos
Autores principales: Huang, Hui-Ting, Chen, Po-See, Kuo, Yu-Min, Tzeng, Shun-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249324/
https://www.ncbi.nlm.nih.gov/pubmed/32450884
http://dx.doi.org/10.1186/s12974-020-01837-x