Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice

BACKGROUND: Fat accumulation in the liver contributes to the development of non-alcoholic fatty liver disease (NAFLD). N-acetylcysteine (NAC) is an antioxidant, acting both directly and indirectly via upregulation of cellular antioxidants. We examined the mechanisms of liver steatosis after 12 month...

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Detalles Bibliográficos
Autores principales: Tsai, Ching-Chou, Chen, Yu-Jen, Yu, Hong-Ren, Huang, Li-Tung, Tain, You-Lin, Lin, I-Chun, Sheen, Jiunn-Ming, Wang, Pei-Wen, Tiao, Mao-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249367/
https://www.ncbi.nlm.nih.gov/pubmed/32450865
http://dx.doi.org/10.1186/s12944-020-01274-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249367/
https://www.ncbi.nlm.nih.gov/pubmed/32450865
http://dx.doi.org/10.1186/s12944-020-01274-y

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