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Interleukin-17 promotes nitric oxide-dependent expression of PD-L1 in mesenchymal stem cells

BACKGROUND: Interleukin-17A (IL-17) is an evolutionary conserved cytokine and best known for its role in boosting immune response. However, recent clinical researches showed that abundant IL-17 in tumor microenvironment was often associated with poor prognosis and reduced cytotoxic T cell infiltrati...

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Detalles Bibliográficos
Autores principales: Wang, Shijia, Wang, Guan, Zhang, Liying, Li, Fengying, Liu, Keli, Wang, Ying, Shi, Yufang, Cao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249370/
https://www.ncbi.nlm.nih.gov/pubmed/32509271
http://dx.doi.org/10.1186/s13578-020-00431-1