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Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice

Glaucoma is the leading cause of irreversible vision loss. Ocular hypertension is a major risk factor for glaucoma and recent work has demonstrated critical early neuroinflammatory insults occur in the optic nerve head following ocular hypertension. Microglia and infiltrating monocytes are likely ca...

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Detalles Bibliográficos
Autores principales: Tribble, James R., Harder, Jeffrey M., Williams, Pete A., John, Simon W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249412/
https://www.ncbi.nlm.nih.gov/pubmed/32450896
http://dx.doi.org/10.1186/s13041-020-00603-7