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Eliminating senescent chondrogenic progenitor cells enhances chondrogenesis under intermittent hydrostatic pressure for the treatment of OA

BACKGROUND: Osteoarthritis (OA) is a major cause of limb dysfunction, and distraction arthroplasty which generates intermittent hydrostatic pressure (IHP) is an effective approach for OA treatment. However, the result was not always satisfactory and the reasons remained unresolved. Because aging is...

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Detalles Bibliográficos
Autores principales: Dai, Hanhao, Chen, Ran, Gui, Chang, Tao, Tianqi, Ge, Yingbin, Zhao, Xilian, Qin, Ran, Yao, Wangxiang, Gu, Song, Jiang, Yiqiu, Gui, Jianchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249424/
https://www.ncbi.nlm.nih.gov/pubmed/32450920
http://dx.doi.org/10.1186/s13287-020-01708-5