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CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant
BACKGROUND: We evaluated the role of CYP3A5, ABCB1 and SXR gene polymorphisms in the occurrence of acute kidney rejection in a cohort of pediatric renal transplant recipients. METHODS: Forty-nine patients were genotyped for CYP3A5, ABCB1 and SXR polymorphisms and evaluated with tacrolimus through le...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249618/ https://www.ncbi.nlm.nih.gov/pubmed/32450827 http://dx.doi.org/10.1186/s12887-020-02152-3 |