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CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant

BACKGROUND: We evaluated the role of CYP3A5, ABCB1 and SXR gene polymorphisms in the occurrence of acute kidney rejection in a cohort of pediatric renal transplant recipients. METHODS: Forty-nine patients were genotyped for CYP3A5, ABCB1 and SXR polymorphisms and evaluated with tacrolimus through le...

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Detalles Bibliográficos
Autores principales:	Turolo, Stefano, Edefonti, Alberto, Ghio, Luciana, Testa, Sara, Morello, William, Montini, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249618/ https://www.ncbi.nlm.nih.gov/pubmed/32450827 http://dx.doi.org/10.1186/s12887-020-02152-3

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