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Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells

SUMMARY: Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge fac...

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Detalles Bibliográficos
Autores principales: El-Gammal, Zaynab, AlOkda, Abdelrahman, Ali, Sameh S., Reda, Asmaa, Magdeldin, Sameh, Mansour, Ragaa, El-Badri, Nagwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250418/
https://www.ncbi.nlm.nih.gov/pubmed/32453737
http://dx.doi.org/10.1371/journal.pone.0232759