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Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes
Diabetes is the leading cause of end-stage renal disease worldwide. Our understanding of the early kidney response to chronic hyperglycemia remains incomplete. To address this, we first investigated the urinary proteomes of otherwise healthy youths with and without type 1 diabetes and subsequently e...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250451/ https://www.ncbi.nlm.nih.gov/pubmed/32453760 http://dx.doi.org/10.1371/journal.pone.0233639 |