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Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes

Diabetes is the leading cause of end-stage renal disease worldwide. Our understanding of the early kidney response to chronic hyperglycemia remains incomplete. To address this, we first investigated the urinary proteomes of otherwise healthy youths with and without type 1 diabetes and subsequently e...

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Detalles Bibliográficos
Autores principales: Van, Julie A. D., Clotet-Freixas, Sergi, Hauschild, Anne-Christin, Batruch, Ihor, Jurisica, Igor, Elia, Yesmino, Mahmud, Farid H., Sochett, Etienne, Diamandis, Eleftherios P., Scholey, James W., Konvalinka, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250451/
https://www.ncbi.nlm.nih.gov/pubmed/32453760
http://dx.doi.org/10.1371/journal.pone.0233639