Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration

The sox2 expressing (sox2(+)) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mammals, we have established a zebrafish severe inj...

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Detalles Bibliográficos
Autores principales: Ye, Zhian, Su, Zhongwu, Xie, Siyu, Liu, Yuye, Wang, Yongqiang, Xu, Xi, Zheng, Yiqing, Zhao, Meng, Jiang, Linjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
https://www.ncbi.nlm.nih.gov/pubmed/32352377
http://dx.doi.org/10.7554/eLife.55771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
https://www.ncbi.nlm.nih.gov/pubmed/32352377
http://dx.doi.org/10.7554/eLife.55771

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