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Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration
The sox2 expressing (sox2(+)) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mammals, we have established a zebrafish severe inj...
Autores principales: | Ye, Zhian, Su, Zhongwu, Xie, Siyu, Liu, Yuye, Wang, Yongqiang, Xu, Xi, Zheng, Yiqing, Zhao, Meng, Jiang, Linjia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250571/ https://www.ncbi.nlm.nih.gov/pubmed/32352377 http://dx.doi.org/10.7554/eLife.55771 |
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