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Regulation of the small GTPase Ran by miR-802 modulates proliferation and metastasis in colorectal cancer cells

BACKGROUND: The small GTPase Ran is upregulated in multiple cancers and fundamental for cancer cell survival and progression, but its significance and molecular mechanisms in colorectal cancer (CRC) remain elusive. METHODS: Ran expression was detected in CRC cell lines and tumour tissues. In vitro a...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Li, Danxiu, Sun, Lina, Shen, Gaofei, Liu, Hao, Guo, Hao, Ge, Minghui, Liang, Junrong, Chen, Ping, Zhou, Jinchi, Cao, Tianyu, Wang, Qi, Gao, Xiaoliang, Tong, Mingfu, Hu, Sijun, Nie, Yongzhan, Fan, Daiming, wang, xin, Zhao, Xiaodi, Lu, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250854/
https://www.ncbi.nlm.nih.gov/pubmed/32210368
http://dx.doi.org/10.1038/s41416-020-0809-7