Kinesin light chain 4 as a new target for lung cancer chemoresistance via targeted inhibition of checkpoint kinases in the DNA repair network

The poor therapeutic efficacy of non-small cell lung cancer (NSCLC) is partly attributed to the acquisition of chemoresistance. To investigate the mechanism underlying this resistance, we examined the potential link between kinesin light chain 4 (KLC4), which we have previously reported to be associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Baek, Jeong-Hwa, Yun, Hong Shik, Kim, Ju-Young, Lee, Janet, Lee, Yeon-Joo, Lee, Chang-Woo, Song, Jie-Young, Ahn, Jiyeon, Park, Jong Kuk, Kim, Jae-Sung, Lee, Kee-Ho, Kim, Eun Ho, Hwang, Sang-Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250887/
https://www.ncbi.nlm.nih.gov/pubmed/32457423
http://dx.doi.org/10.1038/s41419-020-2592-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250887/
https://www.ncbi.nlm.nih.gov/pubmed/32457423
http://dx.doi.org/10.1038/s41419-020-2592-z

Ejemplares similares