The RNA disruption assay is superior to conventional drug sensitivity assays in detecting cytotoxic drugs

Conventional drug sensitivity assays used to screen prospective anti-cancer agents for cytotoxicity monitor biological processes associated with active growth and proliferation, used as proxies of cell viability. However, these assays are unable to distinguish between growth-arrested (but otherwise...

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Detalles Bibliográficos
Autores principales: Mapletoft, Jonathan P. J., St-Onge, Renée J., Guo, Baoqing, Butler, Phillipe, Masilamani, Twinkle J., D’costa, Lavina, Pritzker, Laura B., Parissenti, Amadeo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250890/
https://www.ncbi.nlm.nih.gov/pubmed/32457334
http://dx.doi.org/10.1038/s41598-020-65579-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250890/
https://www.ncbi.nlm.nih.gov/pubmed/32457334
http://dx.doi.org/10.1038/s41598-020-65579-9

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