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P2Y(14) receptor has a critical role in acute gouty arthritis by regulating pyroptosis of macrophages

Nod-like receptor protein 3 (NLRP3)-mediated pyroptosis has a causal role in the pathogenesis of gout. P2Y(14) receptor (P2Y(14)R) distributed in immune cells including macrophages is a Gi-coupled receptor that inhibits the synthesis of cAMP, which has been regarded as a potential regulator of infla...

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Detalles Bibliográficos
Autores principales:	Li, Hanwen, Jiang, Wenjiao, Ye, Shumin, Zhou, Mengze, Liu, Chunxiao, Yang, Xiping, Hao, Kun, Hu, Qinghua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250907/ https://www.ncbi.nlm.nih.gov/pubmed/32457291 http://dx.doi.org/10.1038/s41419-020-2609-7

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