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Progression-free survival as a surrogate for overall survival in oncology trials: a methodological systematic review
BACKGROUND: Progression-free survival (PFS) is a surrogate endpoint widely used for overall survival (OS) in oncology. Validation of PFS as a surrogate must be done for each indication and each intervention. We aimed to identify all studies evaluating the validity of PFS as a surrogate for OS in onc...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250908/ https://www.ncbi.nlm.nih.gov/pubmed/32214230 http://dx.doi.org/10.1038/s41416-020-0805-y |