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Evolutionary analyses reveal independent origins of gene repertoires and structural motifs associated to fast inactivation in calcium-selective TRPV channels

Essential for calcium homeostasis, TRPV5 and TRPV6 are calcium-selective channels belonging to the transient receptor potential (TRP) gene family. In this study, we investigated the evolutionary history of these channels to add an evolutionary context to the already available physiological informati...

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Detalles Bibliográficos
Autores principales: Flores-Aldama, Lisandra, Vandewege, Michael W., Zavala, Kattina, Colenso, Charlotte K., Gonzalez, Wendy, Brauchi, Sebastian E., Opazo, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250927/
https://www.ncbi.nlm.nih.gov/pubmed/32457384
http://dx.doi.org/10.1038/s41598-020-65679-6